Basal Proliferation and Acantholysis May Represent Histological High-Risk Factors for Progression into Invasive Squamous Cell Carcinoma: A Comparison Study in Solid Organ Transplant Recipients and Matched Immunocompetent Patients

Basal Proliferation and Acantholysis May Represent Histological High-Risk Factors for Progression into Invasive Squamous Cell Carcinoma: A Comparison Study in Solid Organ Transplant Recipients and Matched Immunocompetent Patients

Histological risk factors of AKs cannot be directly determined. Recent studies indicate that AKs restricted to the lower third of the epidermis (AK I), with marked basal proliferation (PRO III) and acantholysis, are associated with an increased risk of progression to invasive squamous cell carcinoma...

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Bibliographic Details
Main Authors: Conrad Falkenberg, Thomas Dirschka, Georgia Gilbert, Eggert Stockfleth, Bernhard Homey, Lutz Schmitz
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Cancers
Subjects:
acantholysis
actinic keratosis
basal proliferation
immunosuppression
cutaneous squamous cell carcinoma
solid organ transplant recipients
Online Access:https://www.mdpi.com/2072-6694/15/6/1765

Internet

https://www.mdpi.com/2072-6694/15/6/1765

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