Differential roles of Aβ processing in hypoxia-induced axonal damage
Axonopathy is a common and early phase in neurodegenerative and traumatic CNS diseases. Recent work suggests that amyloid β (Aβ) produced from amyloid precursor protein (APP) may be a critical downstream mediator of CNS axonopathy in CNS diseases, particularly those associated with hypoxia. We criti...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2015-05-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996115000662 |