Molecular Events behind the Selectivity and Inactivation Properties of Model NaK-Derived Ion Channels

Molecular Events behind the Selectivity and Inactivation Properties of Model NaK-Derived Ion Channels

Y55W mutants of non-selective NaK and partly K<sup>+</sup>-selective NaK2K channels have been used to explore the conformational dynamics at the pore region of these channels as they interact with either Na<sup>+</sup> or K<sup>+</sup>. A major conclusion is that...

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Bibliographic Details
Main Authors: Ana Marcela Giudici, María Lourdes Renart, Ana Coutinho, Andrés Morales, José Manuel González-Ros, José Antonio Poveda
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:International Journal of Molecular Sciences
Subjects:
potassium channels
selectivity
inactivation
conformational flexibility
ion binding
thermal stability
Online Access:https://www.mdpi.com/1422-0067/23/16/9246

Internet

https://www.mdpi.com/1422-0067/23/16/9246

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