Telomerase biogenesis requires a novel Mex67 function and a cytoplasmic association with the Sm7 complex

The templating RNA is the core of the telomerase reverse transcriptase. In Saccharomyces cerevisiae, the complex life cycle and maturation of telomerase includes a cytoplasmic stage. However, timing and reason for this cytoplasmic passage are poorly understood. Here, we use inducible RNA tagging exp...

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Bibliographic Details
Main Authors: Yulia Vasianovich, Emmanuel Bajon, Raymund J Wellinger
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-10-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/60000