Placental cytochrome P450 methylomes in infants exposed to prenatal opioids: exploring the effects of neonatal opioid withdrawal syndrome on health horizons

Placental cytochrome P450 methylomes in infants exposed to prenatal opioids: exploring the effects of neonatal opioid withdrawal syndrome on health horizons

Background: Neonatal opioid withdrawal syndrome (NOWS), arises due to increased opioid use during pregnancy. Cytochrome P450 (CYP) enzymes play a pivotal role in metabolizing a wide range of substances in the human body, including opioids, other drugs, toxins, and endogenous compounds. The associati...

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Bibliographic Details
Main Authors: Uppala Radhakrishna, Senthilkumar Sadhasivam, Rupa Radhakrishnan, Ariadna Forray, Srinivas B. Muvvala, Raghu P. Metpally, Saumya Patel, Rakesh M. Rawal, Sangeetha Vishweswaraiah, Ray O. Bahado-Singh, Swapan K. Nath
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Genetics
Subjects:
cytochromes
biomarker
opioid use
neonatal opioid withdrawal syndrome CYP19A1
CYP1A2
CYP4V2
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2023.1292148/full

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https://www.frontiersin.org/articles/10.3389/fgene.2023.1292148/full

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