Toward a Model for Activation of Orai Channel

Toward a Model for Activation of Orai Channel

Summary: Store-operated calcium release-activated calcium (CRAC) channels mediate a variety of cellular signaling functions. The CRAC channel pore-forming protein, Orai1, is a hexamer arranged with 3-fold symmetry. Despite its importance in moving Ca2+ ions into cells, a detailed mechanistic underst...

Full description

Bibliographic Details
Main Authors: Hao Dong, Yiming Zhang, Ruiheng Song, Jingjie Xu, Yigao Yuan, Jindou Liu, Jia Li, Sisi Zheng, Tiantian Liu, Benzhuo Lu, Youjun Wang, Michael L. Klein
Format: Article
Language:English
Published: Elsevier 2019-06-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004219301786

Internet

http://www.sciencedirect.com/science/article/pii/S2589004219301786

Similar Items