Spontaneous xenogeneic GvHD in Wilms' tumor Patient‐Derived xenograft models and potential solutions

Spontaneous xenogeneic GvHD in Wilms' tumor Patient‐Derived xenograft models and potential solutions

Abstract Severely immunocompromised NOD.Cg‐PrkdcscidIl2rgtm1Sug (NOG) mice are among the ideal animal recipients for generation of human cancer models. Transplantation of human solid tumors having abundant tumor‐infiltrating lymphocytes (TILs) can induce xenogeneic graft‐versus‐host disease (xGvHD)...

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Hlavní autoři: Seyed Mostafa Monzavi, Ahad Muhammadnejad, Maryam Behfar, Amir Arsalan Khorsand, Samad Muhammadnejad, Abdol‐Mohammad Kajbafzadeh
Médium: Článek
Jazyk:English
Vydáno: Wiley 2022-08-01
Edice:Animal Models and Experimental Medicine
Témata:
graft‐versus‐host disease
patient‐derived xenograft models
tumor‐infiltrating lymphocytes
Wilms' tumor
On-line přístup:https://doi.org/10.1002/ame2.12254

Internet

https://doi.org/10.1002/ame2.12254

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