The Oxidative Stress-Induced Increase in the Membrane Expression of the Water-Permeable Channel Aquaporin-4 in Astrocytes Is Regulated by Caveolin-1 Phosphorylation

The Oxidative Stress-Induced Increase in the Membrane Expression of the Water-Permeable Channel Aquaporin-4 in Astrocytes Is Regulated by Caveolin-1 Phosphorylation

The reperfusion of ischemic brain tissue following a cerebral stroke causes oxidative stress, and leads to the generation of reactive oxygen species (ROS). Apart from inflicting oxidative damage, the latter may also trigger the upregulation of aquaporin 4 (AQP4), a water-permeable channel expressed...

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Bibliographic Details
Main Authors: Chongshan Bi, Daniel K. L. Tham, Caroline Perronnet, Bharat Joshi, Ivan R. Nabi, Hakima Moukhles
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-12-01
Series:Frontiers in Cellular Neuroscience
Subjects:
reactive oxygen species
oxidative stress
aquaporin 4
caveolin-1
astrocytes
Online Access:http://journal.frontiersin.org/article/10.3389/fncel.2017.00412/full

Internet

http://journal.frontiersin.org/article/10.3389/fncel.2017.00412/full

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