Mycobacteriophage endolysins: diverse and modular enzymes with multiple catalytic activities.

The mycobacterial cell wall presents significant challenges to mycobacteriophages--viruses that infect mycobacterial hosts--because of its unusual structure containing a mycolic acid-rich mycobacterial outer membrane attached to an arabinogalactan layer that is in turn linked to the peptidoglycan. A...

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Bibliographic Details
Main Authors: Kimberly M Payne, Graham F Hatfull
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3314691?pdf=render