Genetic evidence that SMAD2 is not required for gonadal tumor development in inhibin-deficient mice
<p>Abstract</p> <p>Background</p> <p>Inhibin is a tumor-suppressor and activin antagonist. Inhibin-deficient mice develop gonadal tumors and a cachexia wasting syndrome due to enhanced activin signaling. Because activins signal through SMAD2 and SMAD3 in vitro and loss...
| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | English |
| Publicado em: |
BMC
2010-06-01
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| Colecção: | Reproductive Biology and Endocrinology |
| Acesso em linha: | http://www.rbej.com/content/8/1/69 |