Evaluating and improving the representation of bacterial contents in long-read metagenome assemblies

Abstract Background In the metagenomic assembly of a microbial community, abundant species are often thought to assemble well given their deeper sequencing coverage. This conjuncture is rarely tested or evaluated in practice. We often do not know how many abundant species are missing and do not have...

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Bibliographic Details
Main Authors: Xiaowen Feng, Heng Li
Format: Article
Language:English
Published: BMC 2024-04-01
Series:Genome Biology
Subjects:
Online Access:https://doi.org/10.1186/s13059-024-03234-6