New Viral Diseases and New Possible Remedies by Means of the Pharmacology of the Renin-Angiotensin System
All strains of SARS-CoV-2, as well as previously described SARS-CoV and MERS-CoV, bind to ACE2, the cell membrane receptor of β-coronaviruses. Monocarboxypeptidase ACE2 activity stops upon viral entry into cells, leading to inadequate tissue production of angiotensin 1-7 (Ang1-7). Acute lung injury...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publications
2023-01-01
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| Series: | Journal of the Renin-Angiotensin-Aldosterone System |
| Online Access: | http://dx.doi.org/10.1155/2023/3362391 |