Statistical considerations for the platform trial in COVID-19 vaccine priming and boosting

Statistical considerations for the platform trial in COVID-19 vaccine priming and boosting

Abstract The Platform trial In COVID-19 priming and BOOsting (PICOBOO) is a multi-site, adaptive platform trial designed to generate evidence of the immunogenicity, reactogenicity, and cross-protection of different booster vaccination strategies against severe acute respiratory syndrome coronavirus...

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Bibliographic Details
Main Authors: Michael Dymock, Charlie McLeod, Peter Richmond, Tom Snelling, Julie A. Marsh, On behalf of the PICOBOO Investigator Team
Format: Article
Language:English
Published: BMC 2024-07-01
Series:Trials
Subjects:
COVID-19
Vaccine
Adaptive trial
Bayesian
Immunogenicity
Reactogenicity
Online Access:https://doi.org/10.1186/s13063-024-08343-y

Internet

https://doi.org/10.1186/s13063-024-08343-y

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