Mitochondrion of the Trypanosoma brucei long slender bloodstream form is capable of ATP production by substrate-level phosphorylation.

The long slender bloodstream form Trypanosoma brucei maintains its essential mitochondrial membrane potential (ΔΨm) through the proton-pumping activity of the FoF1-ATP synthase operating in the reverse mode. The ATP that drives this hydrolytic reaction has long been thought to be generated by glycol...

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Bibliographic Details
Main Authors: Gergana Taleva, Michaela Husová, Brian Panicucci, Carolina Hierro-Yap, Erika Pineda, Marc Biran, Martin Moos, Petr Šimek, Falk Butter, Frédéric Bringaud, Alena Zíková
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-10-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1011699&type=printable