Paraoxonase 1 (PON1) Q192R genotypes and their interaction with smoking strongly increase atherogenicity and the Framingham risk score
ABSTRACT Objective Paraoxonase 1 (PON1) polymorphisms are associated with an increased susceptibility to cardiovascular disease. PON1 Q192R polymorphism (rs662) partially determine PON1 hydrolytic activity and protect against oxidation of LDL and HDL. This study aimed to delineate the association...
Main Authors: | , , , , , , , , |
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פורמט: | Article |
שפה: | English |
יצא לאור: |
Brazilian Society of Endocrinology and Metabolism
2016-08-01
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סדרה: | Archives of Endocrinology and Metabolism |
נושאים: | |
גישה מקוונת: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972016000500426&lng=en&tlng=en |