Paraoxonase 1 (PON1) Q192R genotypes and their interaction with smoking strongly increase atherogenicity and the Framingham risk score
ABSTRACT Objective Paraoxonase 1 (PON1) polymorphisms are associated with an increased susceptibility to cardiovascular disease. PON1 Q192R polymorphism (rs662) partially determine PON1 hydrolytic activity and protect against oxidation of LDL and HDL. This study aimed to delineate the association...
主要な著者: | , , , , , , , , |
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フォーマット: | 論文 |
言語: | English |
出版事項: |
Brazilian Society of Endocrinology and Metabolism
2016-08-01
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シリーズ: | Archives of Endocrinology and Metabolism |
主題: | |
オンライン・アクセス: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972016000500426&lng=en&tlng=en |