Optical Tweezers with Integrated Multiplane Microscopy (OpTIMuM): a new tool for 3D microrheology

Abstract We introduce a novel 3D microrheology system that combines for the first time Optical Tweezers with Integrated Multiplane Microscopy (OpTIMuM). The system allows the 3D tracking of an optically trapped bead, with ~ 20 nm accuracy along the optical axis. This is achieved without the need for...

Full description

Bibliographic Details
Main Authors: Andrew B. Matheson, Lynn Paterson, Amanda J. Wright, Tania Mendonca, Manlio Tassieri, Paul A. Dalgarno
Format: Article
Language:English
Published: Nature Portfolio 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-85013-y