Zebrafish-based identification of the antiseizure nucleoside inosine from the marine diatom Skeletonema marinoi.

Zebrafish-based identification of the antiseizure nucleoside inosine from the marine diatom Skeletonema marinoi.

With the goal of identifying neuroactive secondary metabolites from microalgae, a microscale in vivo zebrafish bioassay for antiseizure activity was used to evaluate bioactivities of the diatom Skeletonema marinoi, which was recently revealed as being a promising source of drug-like small molecules....

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Bibliographic Details
Main Authors: Théo Brillatz, Chiara Lauritano, Maxime Jacmin, Supitcha Khamma, Laurence Marcourt, Davide Righi, Giovanna Romano, Francesco Esposito, Adrianna Ianora, Emerson F Queiroz, Jean-Luc Wolfender, Alexander D Crawford
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5916873?pdf=render

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http://europepmc.org/articles/PMC5916873?pdf=render

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