MicroRNA profiling in plasma samples using qPCR arrays: Recommendations for correct analysis and interpretation.

MicroRNA (miRNA) regulate gene expression through posttranscriptional mRNA degradation or suppression of translation. Many (pre)analytical issues remain to be resolved for miRNA screening with TaqMan Low Density Arrays (TLDA) in plasma samples, such as optimal RNA isolation, preamplification and dat...

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Bibliographic Details
Main Authors: Andreas B Gevaert, Isabel Witvrouwen, Christiaan J Vrints, Hein Heidbuchel, Emeline M Van Craenenbroeck, Steven J Van Laere, Amaryllis H Van Craenenbroeck
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5825041?pdf=render