Advancements in drug delivery methods for the treatment of brain disease

Advancements in drug delivery methods for the treatment of brain disease

The blood-brain barrier (BBB) presents a formidable obstacle to the effective delivery of systemically administered pharmacological agents to the brain, with ~5% of candidate drugs capable of effectively penetrating the BBB. A variety of biomaterials and therapeutic delivery devices have recently be...

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Bibliographic Details
Main Authors: Brittanie Partridge, Allison Eardley, Brianna E. Morales, Sabrina N. Campelo, Melvin F. Lorenzo, Jason N. Mehta, Yukitaka Kani, Josefa K. Garcia Mora, Etse-Oghena Y. Campbell, Christopher B. Arena, Simon Platt, Akiva Mintz, Richard L. Shinn, Christopher G. Rylander, Waldemar Debinski, Rafael V. Davalos, John H. Rossmeisl
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Veterinary Science
Subjects:
blood-brain barrier
brain tumors
convection enhanced delivery
focused ultrasound
interstitial delivery
nanoparticles
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2022.1039745/full

Internet

https://www.frontiersin.org/articles/10.3389/fvets.2022.1039745/full

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