Subverting Toll-like receptor signalling by bacterial pathogens

Pathogenic bacteria are detected by pattern-recognition receptors (PRRs) expressed on innate immune cells, which activate intracellular signal transduction pathways to elicit an immune response. Toll-like receptors are perhaps the most studied of the PRRs and can activate the Mitogen Activated Prote...

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Bibliographic Details
Main Authors: Victoria eMcGuire, J Simon C Arthur
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-12-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00607/full