The Burden of Post-Translational Modification (PTM)—Disrupting Mutations in the Tumor Matrisome

The Burden of Post-Translational Modification (PTM)—Disrupting Mutations in the Tumor Matrisome

Background: To evaluate the occurrence of mutations affecting post-translational modification (PTM) sites in matrisome genes across different tumor types, in light of their genomic and functional contexts and in comparison with the rest of the genome. Methods: This study spans 9075 tumor samples and...

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Bibliographic Details
Main Authors: Elisa Holstein, Annalena Dittmann, Anni Kääriäinen, Vilma Pesola, Jarkko Koivunen, Taina Pihlajaniemi, Alexandra Naba, Valerio Izzi
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cancers
Subjects:
extracellular matrix (ECM)
matrisome
mutations
post-translational modifications (PTM)
pan-cancer
Online Access:https://www.mdpi.com/2072-6694/13/5/1081

Internet

https://www.mdpi.com/2072-6694/13/5/1081

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