The Ubiquitous Conserved Glycopeptidase Gcp Prevents Accumulation of Toxic Glycated Proteins

ABSTRACT Amadori-modified proteins (AMPs) are the products of nonenzymatic glycation formed by reaction of reducing sugars with primary amine-containing amino acids and can develop into advanced glycated end products (AGEs), highly stable toxic compounds. AGEs are known to participate in many age-re...

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Bibliographic Details
Main Authors: Chen Katz, Ifat Cohen-Or, Uri Gophna, Eliora Z. Ron
Format: Article
Language:English
Published: American Society for Microbiology 2010-08-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.00195-10