Identification of SSRI-evoked antidepressant sensory signals by decoding vagus nerve activity

Abstract The vagus nerve relays mood-altering signals originating in the gut lumen to the brain. In mice, an intact vagus is required to mediate the behavioural effects of both intraluminally applied selective serotonin reuptake inhibitors and a strain of Lactobacillus with antidepressant-like activ...

Full description

Bibliographic Details
Main Authors: Christine L. West, Karen-Anne McVey Neufeld, Yu-Kang Mao, Andrew M. Stanisz, Paul Forsythe, John Bienenstock, Denise Barbut, Michael Zasloff, Wolfgang A. Kunze
Format: Article
Language:English
Published: Nature Portfolio 2021-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-00615-w