MCP-1 and murine prion disease: Separation of early behavioural dysfunction from overt clinical disease
Prion diseases are chronic, fatal neurodegenerative conditions of the CNS. We have investigated the role of monocyte chemoattractant protein-1 (MCP-1) in the ME7 model of murine prion disease. MCP-1 expression increased in the CNS throughout disease progression and was positively correlated with mic...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2005-11-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996105000847 |