Canonical Wnt signaling is not required for Tgfb3 expression in the basal medial edge epithelium during palatogenesis

Canonical Wnt signaling is not required for Tgfb3 expression in the basal medial edge epithelium during palatogenesis

The secondary palate forms from two lateral primordia called the palatal shelves which form a contact in the midline, become adherent at the fusing interface (medial edge epithelia, MEE) and subsequently fuse. The gene encoding transforming growth factor-ß3 (Tgfb3) is strongly and specifically expre...

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Bibliographic Details
Main Authors: Ghazi-Abdullah Saroya, Erica Siismets, Max Hu, Christopher Panaretos, Adam Rice, Kurt Reynolds, Chengji J. Zhou, Vesa Kaartinen
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Physiology
Subjects:
beta-Catenin
TGF-beta3
canonical Wnt signal pathway
palatogenesis
cleft palate (CP)
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2023.704406/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2023.704406/full

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