Simvastatin in the Prevention of Recurrent Pancreatitis: Design and Rationale of a Multicenter Triple-Blind Randomized Controlled Trial, the SIMBA Trial

Simvastatin in the Prevention of Recurrent Pancreatitis: Design and Rationale of a Multicenter Triple-Blind Randomized Controlled Trial, the SIMBA Trial

Background: One in every four patients with a first episode of non-gallstone-related acute pancreatitis (AP) develops recurrent disease. Recurrent episodes of AP or acute flares of chronic pancreatitis (CP) are associated with decreased quality of life and progression of the disease. Besides removin...

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Bibliographic Details
Main Authors: Karina Cárdenas-Jaén, Alicia Vaillo-Rocamora, Ángel Gracia, Pramoud K. Garg, Pedro Zapater, Georgios I. Papachristou, Vikesh K. Singh, Bechien U. Wu, Enrique de-Madaria
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Medicine
Subjects:
hydroxymethylglutaryl-CoA reductase inhibitors
statins
simvastatin
acute pancreatitis
chronic pancreatitis
recurrent
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2020.00494/full

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https://www.frontiersin.org/articles/10.3389/fmed.2020.00494/full

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