Induction of endoplasmic reticulum stress is associated with the anti‐tumor activity of monepantel across cancer types

Abstract Background Monepantel is an anti‐helminthic drug that also has anti‐cancer properties. Despite several studies over the years, the molecular target of monepantel in mammalian cells is still unknown, and its mechanism‐of‐action is not fully understood, though effects on cell cycle, mTOR sign...

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Bibliographic Details
Main Authors: Tiffany J. Harris, Yang Liao, Wei Shi, Marco Evangelista, Bhupinder Pal, Hamsa Puthalakath, Roger Aston, Richard Mollard, John M. Mariadason, Erinna F. Lee, Walter D. Fairlie
Format: Article
Language:English
Published: Wiley 2023-06-01
Series:Cancer Medicine
Subjects:
Online Access:https://doi.org/10.1002/cam4.6021