Soluble AXL is a novel blood marker for early detection of pancreatic ductal adenocarcinoma and differential diagnosis from chronic pancreatitis

Soluble AXL is a novel blood marker for early detection of pancreatic ductal adenocarcinoma and differential diagnosis from chronic pancreatitis

Summary: Background: Early diagnosis is crucial for patients with pancreatic ductal adenocarcinoma (PDAC). The AXL receptor tyrosine kinase is proteolytically processed releasing a soluble form (sAXL) into the blood stream. Here we explore the use of sAXL as a biomarker for PDAC. Methods: AXL was a...

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Bibliographic Details
Main Authors: Neus Martínez-Bosch, Helena Cristóbal, Mar Iglesias, Meritxell Gironella, Luis Barranco, Laura Visa, Domenico Calafato, Silvia Jiménez-Parrado, Julie Earl, Alfredo Carrato, Noemí Manero-Rupérez, Mireia Moreno, Albert Morales, Carmen Guerra, Pilar Navarro, Pablo García de Frutos
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:EBioMedicine
Subjects:
PDAC
AXL
Pancreas
Biomarker
Differential diagnosis
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396421005910

Internet

http://www.sciencedirect.com/science/article/pii/S2352396421005910

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