Gender dimorphism in hepatocarcinogenesis—DNA methylation modification regulated X‐chromosome inactivation escape molecule XIST

Gender dimorphism in hepatocarcinogenesis—DNA methylation modification regulated X‐chromosome inactivation escape molecule XIST

Abstract Background Sex disparities constitute a significant issue in hepatocellular carcinoma (HCC). However, the mechanism of gender dimorphism in HCC is still not completely understood. Methods 5‐Hydroxymethylcytosine (5hmC)‐Seal technology was utilised to detect the global 5hmC levels from four...

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Bibliographic Details
Main Authors: Zhihui Dai, Sijie Wang, Xinggang Guo, Yuefan Wang, Haozan Yin, Jian Tan, Chenyang Mu, Shu‐Han Sun, Hui Liu, Fu Yang
Format: Article
Language:English
Published: Wiley 2023-12-01
Series:Clinical and Translational Medicine
Subjects:
DNA methylation
hepatocellular carcinoma
TET2
XIST
Online Access:https://doi.org/10.1002/ctm2.1518

Internet

https://doi.org/10.1002/ctm2.1518

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