Utilizing hot-stage polarized microscopy and ATR-FTIR for ramipril co-crystal screening, supported by principal component analysis and cluster analysis

Utilizing hot-stage polarized microscopy and ATR-FTIR for ramipril co-crystal screening, supported by principal component analysis and cluster analysis

Context: Co-crystal formation, a method for enhancing the physicochemical properties of active pharmaceutical ingredients (APIs), has gained traction in pharmaceutical research. However, the current landscape lacks comprehensive and dependable co-crystal screening methods. Aims: To implement and...

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Bibliographic Details
Main Authors: Indra Indra, Saleh Wikarsa, Yuda Prasetya Nugraha, Veinardi Suendo, Hidehiro Uekusa, Sundani Nurono Soewandhi
Format: Article
Language:English
Published: GarVal Editorial Ltda. 2023-11-01
Series:Journal of Pharmacy & Pharmacognosy Research
Subjects:
anthranilic acid
crystallization
isonicotinamide
multivariate analysis
vanillin
x-ray diffraction
Online Access:https://jppres.com/jppres/pdf/vol11/jppres23.1723_11.6.1137.pdf

Internet

https://jppres.com/jppres/pdf/vol11/jppres23.1723_11.6.1137.pdf

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