OCTN2- and ATB0,+-targeted nanoemulsions for improving ocular drug delivery

OCTN2- and ATB0,+-targeted nanoemulsions for improving ocular drug delivery

Abstract Traditional eye drops are administered via topical instillation. However, frequent dosing is needed due to their relatively rapid precorneal removal and low ocular bioavailability. To address these issues, stearoyl L-carnitine-modified nanoemulsions (SC-NEs) were fabricated. The physicochem...

Full description

Bibliographic Details
Main Authors: Bo Tang, Qiuxiang Wang, Guowei Zhang, Aiwen Zhang, Lu Zhu, Rongrong Zhao, Hongwei Gu, Jie Meng, Junfang Zhang, Guihua Fang
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Journal of Nanobiotechnology
Subjects:
Stearoyl l-carnitine
Nanoemulsions
Novel organic cation/carnitine transporter 2 (OCTN2)
Amino acid transporter B (0 +) (ATB0,+)
Endotoxin-induced uveitis
Ocular drug bioavailability
Online Access:https://doi.org/10.1186/s12951-024-02402-x

Internet

https://doi.org/10.1186/s12951-024-02402-x

Similar Items