Increased soluble CD4 in serum of rheumatoid arthritis patients is generated by matrix metalloproteinase (MMP)-like proteinases.

Increased soluble CD4 in serum of rheumatoid arthritis patients is generated by matrix metalloproteinase (MMP)-like proteinases.

Higher soluble CD4 (sCD4) levels in serum have been detected in patients of infectious and chronic inflammatory diseases. However, how and why sCD4 is produced remains poorly understood. We establish sensitive ELISA and WB assays for sCD4 detection in conditioned medium of in vitro cell culture syst...

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Bibliographic Details
Main Authors: Wen-Yi Tseng, Yi-Shu Huang, Nien-Yi Chiang, Yeh-Pin Chou, Yeong-Jian Jan Wu, Shue-Fen Luo, Chang-Fu Kuo, Ko-Ming Lin, Hsi-Hsien Lin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3660307?pdf=render

Internet

http://europepmc.org/articles/PMC3660307?pdf=render

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