NF-κB-regulated VentX expression mediates tumoricidal effects of chemotherapeutics at noncytotoxic concentrations

NF-κB-regulated VentX expression mediates tumoricidal effects of chemotherapeutics at noncytotoxic concentrations

Summary: Limited therapeutic efficacy and severe side effects represent the central hurdles facing cancer chemotherapy. Immune suppression within tumor immune microenvironments (TIME) has been implicated in chemoresistance. In this study, using a TIME-enabling model system (TIME-EMS), we demonstrate...

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Bibliographic Details
Main Authors: Yi Le, Hong Gao, Angie Zhu, Kristen Felt, Scott Rodig, Ronald Bleday, Zhenglun Zhu
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:iScience
Subjects:
Molecular biology
Immunology
Cell biology
Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222016984

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http://www.sciencedirect.com/science/article/pii/S2589004222016984

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