Scaffold-free tissue engineering for injured joint surface restoration

Abstract Articular cartilage does not heal spontaneously due to its limited healing capacity, and thus effective treatments for cartilage injuries has remained challenging. Since the first report by Brittberg et al. in 1994, autologous chondrocyte implantation (ACI) has been introduced into the clin...

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Bibliographic Details
Main Authors: Kazunori Shimomura, Wataru Ando, Hiromichi Fujie, David A. Hart, Hideki Yoshikawa, Norimasa Nakamura
Format: Article
Language:English
Published: SpringerOpen 2018-01-01
Series:Journal of Experimental Orthopaedics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s40634-017-0118-0