HupA, the main undecaprenyl pyrophosphate and phosphatidylglycerol phosphate phosphatase in Helicobacter pylori is essential for colonization of the stomach.

HupA, the main undecaprenyl pyrophosphate and phosphatidylglycerol phosphate phosphatase in Helicobacter pylori is essential for colonization of the stomach.

The biogenesis of bacterial cell-envelope polysaccharides requires the translocation, across the plasma membrane, of sugar sub-units that are produced inside the cytoplasm. To this end, the hydrophilic sugars are anchored to a lipid phosphate carrier (undecaprenyl phosphate (C55-P)), yielding membra...

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Bibliographic Details
Main Authors: Elise Gasiorowski, Rodolphe Auger, Xudong Tian, Samia Hicham, Chantal Ecobichon, Sophie Roure, Martin V Douglass, M Stephen Trent, Dominique Mengin-Lecreulx, Thierry Touzé, Ivo Gomperts Boneca
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-09-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1007972

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https://doi.org/10.1371/journal.ppat.1007972

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