Humanizing Miniature Hearts through 4-Flow Cannulation Perfusion Decellularization and Recellularization

Humanizing Miniature Hearts through 4-Flow Cannulation Perfusion Decellularization and Recellularization

Abstract Despite improvements in pre-clinical drug testing models, predictability of clinical outcomes continues to be inadequate and costly due to poor evidence of drug metabolism. Humanized miniature organs integrating decellularized rodent organs with tissue specific cells are translational model...

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Bibliographic Details
Main Authors: Duong T. Nguyen, Matthew O’Hara, Cecilia Graneli, Ryan Hicks, Tasso Miliotis, Ann-Christin Nyström, Sara Hansson, Pia Davidsson, Li-Ming Gan, Maria Chiara Magnone, Magnus Althage, Sepideh Heydarkhan-Hagvall
Format: Article
Language:English
Published: Nature Portfolio 2018-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-25883-x

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https://doi.org/10.1038/s41598-018-25883-x

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