Metabolic Stress Impairs Pericyte Response to Optogenetic Stimulation in Pancreatic Islets

Metabolic Stress Impairs Pericyte Response to Optogenetic Stimulation in Pancreatic Islets

Pancreatic islets are highly vascularized micro-organs ensuring whole body glucose homeostasis. Islet vascular cells play an integral part in sustaining adequate insulin release by beta cells. In particular, recent studies have demonstrated that islet pericytes regulate local blood flow velocity and...

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Bibliographic Details
Main Authors: Aurélien Michau, Chrystel Lafont, Paula Bargi-Souza, Yasmine Kemkem, Anne Guillou, Magalie A. Ravier, Gyslaine Bertrand, Annie Varrault, Tatiana Fiordelisio, David J. Hodson, Patrice Mollard, Marie Schaeffer
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Endocrinology
Subjects:
diabetes
vessel
pericyte
optogenetics
pancreas
imaging
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.918733/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2022.918733/full

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