Long-Term Dietary Taurine Lowers Plasma Levels of Cholesterol and Bile Acids

Long-Term Dietary Taurine Lowers Plasma Levels of Cholesterol and Bile Acids

Cholesterol is an essential lipid in vertebrates, but excess blood cholesterol promotes atherosclerosis. In the liver, cholesterol is metabolized to bile acids by cytochrome P450, family 7, subfamily a, polypeptide 1 (CYP7A1), the transcription of which is negatively regulated by the ERK pathway. Fi...

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Bibliographic Details
Main Authors: Ryoma Tagawa, Masaki Kobayashi, Misako Sakurai, Maho Yoshida, Hiroki Kaneko, Yuhei Mizunoe, Yuka Nozaki, Naoyuki Okita, Yuka Sudo, Yoshikazu Higami
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:International Journal of Molecular Sciences
Subjects:
taurine
cholesterol
bile acid
FGF21
ERK
CYP7A1
Online Access:https://www.mdpi.com/1422-0067/23/3/1793

Internet

https://www.mdpi.com/1422-0067/23/3/1793

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