Topoisomerase Induced DNA Damage Coupled Diseases and Therapeutic Potential

Topoisomerase is an essential enzyme which regulates the topological state of DNA supercoils during replication and transcription. Topoisomerases cleave either one or two DNA strands and then re-join the cleaved strands after passing the intact strand or a double strand through the gap respectively....

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Bibliographic Details
Main Authors: Madhurima Dutta, Somnath Mandal
Format: Article
Language:English
Published: "Vikol publishing" ST Kolesnichenko V.V. 2024-08-01
Series:Journal of Stress Physiology & Biochemistry
Subjects:
Online Access:http://www.jspb.ru/issues/2024/N3/JSPB_2024_3_122-139.pdf