5-Bromoprotocatechualdehyde Combats against Palmitate Toxicity by Inhibiting Parkin Degradation and Reducing ROS-Induced Mitochondrial Damage in Pancreatic β-Cells

Pancreatic β-cell loss is critical in diabetes pathogenesis. Up to now, no effective treatment has become available for β-cell loss. A polyphenol recently isolated from <i>Polysiphonia japonica</i>, 5-Bromoprotocatechualdehyde (BPCA), is considered as a potential compound for the protect...

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Bibliographic Details
Main Authors: Seon-Heui Cha, Chunying Zhang, Soo-Jin Heo, Hee-Sook Jun
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Antioxidants
Subjects:
Online Access:https://www.mdpi.com/2076-3921/10/2/264