A CRISPR-strategy for the generation of a detectable fluorescent hESC reporter line (WAe009-A-37) for the subpallial determinant GSX2

A CRISPR-strategy for the generation of a detectable fluorescent hESC reporter line (WAe009-A-37) for the subpallial determinant GSX2

GSX2 is a homeobox transcription factor (TF) controlling the specification of the ventral lateral ganglionic eminence and its major derivative, the corpus striatum. Medium spiny neurons (MSNs) represent the largest cell component of the striatum and they are primarily affected in Huntington disease...

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Bibliographic Details
Main Authors: Dario Besusso, Andrea Cossu, Ayat Mohamed, Manuel Cernigoj, Paolo Codega, Maura Galimberti, Ilaria Campus, Paola Conforti, Elena Cattaneo
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506120303172

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http://www.sciencedirect.com/science/article/pii/S1873506120303172

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