Clinical Impact of Polygenic Risk Score for Breast Cancer Risk Prediction in 382 Individuals with Hereditary Breast and Ovarian Cancer Syndrome

Clinical Impact of Polygenic Risk Score for Breast Cancer Risk Prediction in 382 Individuals with Hereditary Breast and Ovarian Cancer Syndrome

Single nucleotide polymorphisms are currently not considered in breast cancer (BC) risk predictions used in daily practice of genetic counselling and clinical management of familial BC in Germany. This study aimed to assess the clinical value of incorporating a 313-variant-based polygenic risk score...

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Bibliographic Details
Main Authors: Sarah Stiller, Stephan Drukewitz, Kathleen Lehmann, Julia Hentschel, Vincent Strehlow
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Cancers
Subjects:
breast cancer
risk prediction
polygenic risk score
genetic counselling
hereditary breast and ovarian cancer syndrome
Online Access:https://www.mdpi.com/2072-6694/15/15/3938

Internet

https://www.mdpi.com/2072-6694/15/15/3938

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