Inflammatory profile of eosinophils in asthma-COPD overlap and eosinophilic COPD: a multi-omics study

Inflammatory profile of eosinophils in asthma-COPD overlap and eosinophilic COPD: a multi-omics study

IntroductionElevated blood eosinophil levels in patients with chronic obstructive pulmonary disease (COPD) with or without asthma are linked to increased exacerbations and the effectiveness of inhaled corticosteroid treatment. This study aimed to delineate the inflammatory cellular properties of eos...

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Main Authors: Keeya Sunata, Jun Miyata, Yusuke Kawashima, Ryo Konno, Masaki Ishikawa, Yoshinori Hasegawa, Ryuta Onozato, Yo Otsu, Emiko Matsuyama, Hisashi Sasaki, Shinichi Okuzumi, Takao Mochimaru, Katsunori Masaki, Hiroki Kabata, Shotaro Chubachi, Makoto Arita, Koichi Fukunaga
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-10-01
Series:Frontiers in Immunology
Subjects:
asthma-COPD overlap
chronic obstructive pulmonary disease
eosinophil
IL-33
interferon-γ
multi-omics
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1445769/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2024.1445769/full

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