Hemozoin induces hepatic inflammation in mice and is differentially associated with liver pathology depending on the Plasmodium strain.

Malaria is a global disease that clinically affects more than two hundred million people annually. Despite the availability of effective antimalarials, mortality rates associated with severe complications are high. Hepatopathy is frequently observed in patients with severe malarial disease and its p...

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Main Authors: Katrien Deroost, Natacha Lays, Thao-Thy Pham, Denisa Baci, Kathleen Van den Eynde, Mina Komuta, Mauro Prato, Tania Roskams, Evelin Schwarzer, Ghislain Opdenakker, Philippe E Van den Steen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0113519&type=printable