Tumor immune microenvironment and apoptotic markers in breast cancer patients carrying <I>BRCA1</I> gene mutations

Background. It is suggested that defects in BRCA1 / 2 genes contribute to a high mutational load and high immunogenicity, which modulates immune microenvironment. At the same time, it was shown that BRCA1 / 2-associated breast cancer tumors do not belong to the category of immunoactive ones. These t...

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Bibliographic Details
Main Authors: A. I. Stukan, A. Yu. Goryainova, O. Yu. Chukhray, S. D. Maksimenko, E. N. Imyanitov, S. V. Sharov, Z. K. Khachmamuk
Format: Article
Language:Russian
Published: ABV-press 2022-09-01
Series:Опухоли женской репродуктивной системы
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Online Access:https://ojrs.abvpress.ru/ojrs/article/view/967