Neurodegeneration and microtubule dynamics: Death by a thousand cuts

Neurodegeneration and microtubule dynamics: Death by a thousand cuts

Microtubules form important cytoskeletal structures that play a role in establishing and maintaining neuronal polarity, regulating neuronal morphology, transporting cargo and scaffolding signaling molecules to form signaling hubs. Within a neuronal cell, microtubules are found to have variable lengt...

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Bibliographic Details
Main Authors: Jyoti eDubey, Neena eRatnakaran, Sandhya Padmanabhan Koushika
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-09-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Parkinson Disease
Alzheimer's disease
dying back
Microtuble stability
hyperstable microtubules
microtubule signaling hubs
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00343/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00343/full

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