Adaptation of Imaging Mass Cytometry to Explore the Single Cell Alloimmune Landscape of Liver Transplant Rejection

Adaptation of Imaging Mass Cytometry to Explore the Single Cell Alloimmune Landscape of Liver Transplant Rejection

Rejection continues to be an important cause of graft loss in solid organ transplantation, but deep exploration of intragraft alloimmunity has been limited by the scarcity of clinical biopsy specimens. Emerging single cell immunoprofiling technologies have shown promise in discerning mechanisms of a...

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Bibliographic Details
Main Authors: Nolan Ung, Cameron Goldbeck, Cassandra Man, Julianne Hoeflich, Ren Sun, Arianna Barbetta, Naim Matasci, Jonathan Katz, Jerry S. H. Lee, Shefali Chopra, Shahab Asgharzadeh, Mika Warren, Linda Sher, Rohit Kohli, Omid Akbari, Yuri Genyk, Juliet Emamaullee
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Immunology
Subjects:
single cell analysis
imaging mass cytometry (IMC)
CyTOF mass cytometry
allograft rejection
clinical transplantation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.831103/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.831103/full

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