Moderate exercise mitigates cardiac dysfunction and injury induced by cyclosporine A through activation of the PGI2 / PPAR-γ signaling pathway

Moderate exercise mitigates cardiac dysfunction and injury induced by cyclosporine A through activation of the PGI2 / PPAR-γ signaling pathway

Background and purpose: The present study investigated the role of the prostaglandin I2/peroxisome proliferator activator receptor (PGI2/PPAR) signaling pathway in cardiac cell proliferation, apoptosis, and systemic hemodynamic variables under cyclosporine A (CsA) exposure alone or combined with mod...

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Bibliographic Details
Main Authors: Khatereh Nourmohammadi, Abolfazl Bayrami, Roya Naderi, Alireza Shirpoor, Hamid Soraya
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-01-01
Series:Research in Pharmaceutical Sciences
Subjects:
cyclosporine; exercise; heart; pgi2/ppar signaling pathway; proliferation.
Online Access:http://www.rpsjournal.net/article.asp?issn=1735-5362;year=2023;volume=18;issue=6;spage=696;epage=707;aulast=Nourmohammadi

Internet

http://www.rpsjournal.net/article.asp?issn=1735-5362;year=2023;volume=18;issue=6;spage=696;epage=707;aulast=Nourmohammadi

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