Functions of 1,25-dihydroxy vitamin D3, vitamin D3 receptor and interleukin-22 involved in pathogenesis of gout arthritis through altering metabolic pattern and inflammatory responses

Background Gouty arthritis (GA) is a common type of inflammatory arthritis. Recent studies demonstrated that 1,25-dihydroxy vitamin D3 (1,25(OH) 2 VD3) and vitamin D3 receptor (VD-R) play a protective role in acute inflammation, but interleukin-22(IL-22) promotes inflammation, especially for arthrit...

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Bibliographic Details
Main Authors: Yuqi Chen, Huiya Ma, Youwei Du, Jianjian Dong, Chenkai Jin, Lihui Tan, Rong Wei
Format: Article
Language:English
Published: PeerJ Inc. 2021-12-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/12585.pdf